2VFD

Crystal structure of the F96S mutant of Plasmodium falciparum triosephosphate isomerase

2VFD の概要

• エントリーDOI: 10.2210/pdb2vfd/pdb
• 関連するPDBエントリー: 1LYX 1LZO 1M7O 1M7P 1O5X 1VGA 1WOA 1WOB 1YDV 2VFF 2VFG 2VFH 2VFI
• 分子名称: TRIOSEPHOSPHATE ISOMERASE, SULFATE ION (3 entities in total)
• 機能のキーワード: plasmodium falciparum, fatty acid biosynthesis, triosephosphate isomerase, pentose shunt, gluconeogenesis, lipid synthesis, tim, mutant, loop open, isomerase, glycolysis
• 由来する生物種: PLASMODIUM FALCIPARUM (MALARIAL PARASITE)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 56067.41

構造登録者

Gayathri, P.,Banerjee, M.,Vijayalakshmi, A.,Balaram, H.,Balaram, P.,Murthy, M.R.N. (登録日: 2007-11-03, 公開日: 2008-12-09, 最終更新日: 2023-12-13)

• 主引用文献: Gayathri, P.,Banerjee, M.,Vijayalakshmi, A.,Balaram, H.,Balaram, P.,Murthy, M.R.N.; Biochemical and Structural Characterization of Residue 96 Mutants of Plasmodium Falciparum Triosephosphate Isomerase: Active-Site Loop Conformation, Hydration and Identification of a Dimer-Interface Ligand-Binding Site.; Acta Crystallogr.,Sect.D, 65:847-, 2009; PubMed: 19622869; DOI: 10.1107/S0907444909018666

実験手法

X-RAY DIFFRACTION (1.4 Å)