2VCS

Structure of isoniazid (INH) bound to cytosolic soybean ascorbate peroxidase mutant H42A

Summary for 2VCS

Entry DOI	10.2210/pdb2vcs/pdb
Related	1OAF 1OAG 1V0H 2CL4 2GGN 2GHC 2GHD 2GHE 2GHH 2GHK 2VCF 2VCN
Descriptor	ASCORBATE PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, 4-(DIAZENYLCARBONYL)PYRIDINE, ... (5 entities in total)
Functional Keywords	ascorbate peroxidase, peroxidase, inh, apx, isoniazid, oxidoreductase
Biological source	GLYCINE MAX (SOYBEAN)
Total number of polymer chains	1
Total formula weight	29277.63
Authors	Metcalfe, C.L.,Macdonald, I.K.,Brown, K.A.,Raven, E.L.,Moody, P.C.E. (deposition date: 2007-09-26, release date: 2007-12-04, Last modification date: 2023-12-13)
Primary citation	Metcalfe, C.L.,Macdonald, I.K.,Murphy, E.J.,Brown, K.A.,Raven, E.L.,Moody, P.C.E. The Tuberculosis Prodrug Isoniazid Bound to Activating Peroxidases. J.Biol.Chem., 283:6193-, 2008 Cited by PubMed: 18056997 DOI: 10.1074/JBC.M707412200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.68 Å)

Structure validation