2V62

Structure of vaccinia-related kinase 2

2V62 の概要

• エントリーDOI: 10.2210/pdb2v62/pdb
• 分子名称: SERINE/THREONINE-PROTEIN KINASE VRK2, MAGNESIUM ION, SUCCINIC ACID, ... (5 entities in total)
• 機能のキーワード: transferase, atp-binding, membrane, nucleotide-binding, transmembrane
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Isoform 1: Cytoplasm. Isoform 2: Cytoplasm: Q86Y07
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 78848.38

構造登録者

Bunkoczi, G.,Eswaran, J.,Cooper, C.,Fedorov, O.,Keates, T.,Rellos, P.,Salah, E.,Savitsky, P.,Ugochukwu, E.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Sundstrom, M.,Weigelt, J.,Knapp, S. (登録日: 2007-07-13, 公開日: 2007-08-21, 最終更新日: 2023-12-13)

• 主引用文献: Scheeff, E.D.,Eswaran, J.,Bunkoczi, G.,Knapp, S.,Manning, G.; Structure of the Pseudokinase Vrk3 Reveals a Degraded Catalytic Site, a Highly Conserved Kinase Fold, and a Putative Regulatory Binding Site.; Structure, 17:128-, 2009; PubMed: 19141289; DOI: 10.1016/J.STR.2008.10.018

実験手法

X-RAY DIFFRACTION (1.7 Å)