2V5Q

CRYSTAL STRUCTURE OF WILD-TYPE PLK-1 KINASE DOMAIN IN COMPLEX WITH A SELECTIVE DARPIN

2V5Q の概要

• エントリーDOI: 10.2210/pdb2v5q/pdb
• 関連するPDBエントリー: 1Q4K 1Q4O 1UMW
• 分子名称: SERINE/THREONINE-PROTEIN KINASE PLK1, DESIGN ANKYRIN REPEAT PROTEIN (3 entities in total)
• 機能のキーワード: design ankyrin repeat protein, transferase complex, phosphorylation, nucleotide-binding, serine/threonine-protein kinase, kinase, nucleus, transferase, atp-binding, serine/threonine protein kinase
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 107617.68

構造登録者

Bandeiras, T.M.,Hillig, R.C.,Matias, P.M.,Eberspaecher, U.,Fanghaenel, J.,Thomaz, M.,Miranda, S.,Crusius, K.,Puetter, V.,Amstutz, P.,Gulotti-Georgieva, M.,Binz, H.K.,Holz, C.,Schmitz, A.A.P.,Lang, C.,Donner, P.,Egner, U.,Carrondo, M.A.,Mueller-Tiemann, B. (登録日: 2007-07-08, 公開日: 2008-04-01, 最終更新日: 2023-12-13)

• 主引用文献: Bandeiras, T.M.,Hillig, R.C.,Matias, P.M.,Eberspaecher, U.,Fanghanel, J.,Thomaz, M.,Miranda, S.,Crusius, K.,Putter, V.,Amstutz, P.,Gulotti-Georgieva, M.,Binz, H.K.,Holz, C.,Schmitz, A.A.,Lang, C.,Donner, P.,Egner, U.,Carrondo, M.A.,Muller-Tiemann, B.; Structure of wild-type Plk-1 kinase domain in complex with a selective DARPin.; Acta Crystallogr. D Biol. Crystallogr., 64:339-353, 2008; PubMed: 18391401; DOI: 10.1107/S0907444907068217

実験手法

X-RAY DIFFRACTION (2.3 Å)