2V4B
Crystal Structure of Human ADAMTS-1 catalytic Domain and Cysteine- Rich Domain (apo-form)
Summary for 2V4B
Entry DOI | 10.2210/pdb2v4b/pdb |
Related | 2JIH |
Descriptor | ADAMTS-1, ZINC ION, CADMIUM ION, ... (7 entities in total) |
Functional Keywords | zymogen, protease, adamts-1, hydrolase, metalloprotease, heparin-binding, metalloproteinase, metzincin, glycoprotein, metal-binding, extracellular matrix, cleavage on pair of basic residues |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 67390.92 |
Authors | Gerhardt, S.,Hassall, G.,Hawtin, P.,McCall, E.,Flavell, L.,Minshull, C.,Hargreaves, D.,Ting, A.,Pauptit, R.A.,Parker, A.E.,Abbott, W.M. (deposition date: 2007-06-28, release date: 2008-01-15, Last modification date: 2019-04-24) |
Primary citation | Gerhardt, S.,Hassall, G.,Hawtin, P.,Mccall, E.,Flavell, L.,Minshull, C.,Hargreaves, D.,Ting, A.,Pauptit, R.A.,Parker, A.E.,Abbott, W.M. Crystal Structures of Human Adamts-1 Reveal a Conserved Catalytic Domain and a Disintegrin-Like Domain with a Fold Homologous to Cysteine-Rich Domains. J.Mol.Biol., 373:891-, 2007 Cited by PubMed: 17897672DOI: 10.1016/J.JMB.2007.07.047 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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