2V3O

Thrombin with 3-cycle with F

Summary for 2V3O

• Entry DOI: 10.2210/pdb2v3o/pdb
• Related: 2V3H
• Related PRD ID: PRD_000481
• Descriptor: THROMBIN HEAVY CHAIN, HIRUDIN IIA, THROMBIN LIGHT CHAIN, ... (7 entities in total)
• Functional Keywords: serine protease inhibitor complex, blood clotting, cleavage on pair of basic residues, serine protease inhibitor, disease mutation, blood coagulation, sulfation, acute phase, glycoprotein, gamma-carboxyglutamic acid, serine protease, calcium-binding, protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Secreted, extracellular space: P00734 P00734; Secreted: P01050
• Total number of polymer chains: 3
• Total formula weight: 34801.83

Authors

Banner, D.W.,Wessel, H.P. (deposition date: 2007-06-19, release date: 2008-06-24, Last modification date: 2013-10-23)

• Primary citation: Mueller, K.,Faeh, C.,Diederich, F.; Fluorine in Pharmaceuticals: Looking Beyond Intuition.; Science, 317:1881-, 2007; PubMed: 17901324; DOI: 10.1126/SCIENCE.1131943

Experimental method

X-RAY DIFFRACTION (1.79 Å)