2V3O
Thrombin with 3-cycle with F
Summary for 2V3O
Entry DOI | 10.2210/pdb2v3o/pdb |
Related | 2V3H |
Related PRD ID | PRD_000481 |
Descriptor | THROMBIN HEAVY CHAIN, HIRUDIN IIA, THROMBIN LIGHT CHAIN, ... (7 entities in total) |
Functional Keywords | serine protease inhibitor complex, blood clotting, cleavage on pair of basic residues, serine protease inhibitor, disease mutation, blood coagulation, sulfation, acute phase, glycoprotein, gamma-carboxyglutamic acid, serine protease, calcium-binding, protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Secreted, extracellular space: P00734 P00734 Secreted: P01050 |
Total number of polymer chains | 3 |
Total formula weight | 34801.83 |
Authors | Banner, D.W.,Wessel, H.P. (deposition date: 2007-06-19, release date: 2008-06-24, Last modification date: 2013-10-23) |
Primary citation | Mueller, K.,Faeh, C.,Diederich, F. Fluorine in Pharmaceuticals: Looking Beyond Intuition. Science, 317:1881-, 2007 Cited by PubMed: 17901324DOI: 10.1126/SCIENCE.1131943 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.79 Å) |
Structure validation
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