2V30
Human orotidine 5'-phosphate decarboxylase domain of uridine monophospate synthetase (UMPS) in complex with its product UMP.
Summary for 2V30
Entry DOI | 10.2210/pdb2v30/pdb |
Related | 2JGY |
Descriptor | OROTIDINE 5'-PHOSPHATE DECARBOXYLASE, URIDINE-5'-MONOPHOSPHATE (3 entities in total) |
Functional Keywords | alternative splicing, pyrimidine metabolism, disease mutation, glycosyltransferase, ump, lyase, transferase, polymorphism, decarboxylase, multifunctional enzyme, pyrimidine biosynthesis |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 61910.83 |
Authors | Moche, M.,Ogg, D.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Dahlgren, L.G.,Edwards, A.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg-Schiavone, L.,Johansson, I.,Kallas, A.,Karlberg, T.,Kotenyova, T.,Lehtio, L.,Nyman, T.,Persson, C.,Sagemark, J.,Stenmark, P.,Sundstrom, M.,Thorsell, A.G.,van den Berg, S.,Weigelt, J.,Welin, M.,Nordlund, P.,Structural Genomics Consortium (SGC) (deposition date: 2007-06-10, release date: 2007-07-24, Last modification date: 2023-12-13) |
Primary citation | Moche, M.,Ogg, D.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Dahlgren, L.G.,Edwards, A.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg-Schiavone, L.,Johansson, I.,Kallas, A.,Karlberg, T.,Kotenyova, T.,Lehtio, L.,Nyman, T.,Persson, C.,Sagemark, J.,Stenmark, P.,Sundstrom, M.,Thorsell, A.G.,van den Berg, S.,Weigelt, J.,Welin, M.,Nordlund, P. The Crystal Structure of Human Orotidine 5'-Decarboxylase Domain of Human Uridine Monophosphate Synthetase (Umps) To be Published, |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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