2UZH
Mycobacterium smegmatis 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase (IspF)
Summary for 2UZH
Entry DOI | 10.2210/pdb2uzh/pdb |
Descriptor | 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE, ZINC ION, CYTIDINE-5'-DIPHOSPHATE, ... (9 entities in total) |
Functional Keywords | ispf, lyase, mycobacteria, complex with cdp, non-mevalonate pathway of isoprenoid biosynthesis |
Biological source | MYCOBACTERIUM SMEGMATIS |
Total number of polymer chains | 3 |
Total formula weight | 52600.31 |
Authors | Buetow, L.,Brown, A.C.,Parish, T.,Hunter, W.N. (deposition date: 2007-04-27, release date: 2007-11-06, Last modification date: 2023-12-13) |
Primary citation | Buetow, L.,Brown, A.C.,Parish, T.,Hunter, W.N. The Structure of Mycobacteria 2C-Methyl-D-Erythritol-2,4-Cyclodiphosphate Synthase, an Essential Enzyme, Provides a Platform for Drug Discovery. Bmc Struct.Biol., 7:68-, 2007 Cited by PubMed: 17956607DOI: 10.1186/1472-6807-7-68 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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