2UYX
metallo-beta-lactamase (1BC2) single point mutant D120S
Summary for 2UYX
Entry DOI | 10.2210/pdb2uyx/pdb |
Related | 1BC2 1BMC 1BVT 1DXK 1MQO 2BC2 2BFK 2BFL 2BFZ 2BG2 2BG6 2BG7 2BG8 2BGA 3BC2 |
Descriptor | BETA-LACTAMASE II, GLYCEROL, ZINC ION, ... (4 entities in total) |
Functional Keywords | hydrolase, penicillinase, metal-binding, antibiotic resistance, metallo beta- lactamase |
Biological source | BACILLUS CEREUS |
Total number of polymer chains | 1 |
Total formula weight | 25537.80 |
Authors | Larrull, L.I.,Fabiane, S.M.,Kowalski, J.M.,Bennett, B.,Sutton, B.J.,Vila, A.J. (deposition date: 2007-04-20, release date: 2007-05-08, Last modification date: 2023-12-13) |
Primary citation | Llarrull, L.I.,Fabiane, S.M.,Kowalski, J.M.,Bennett, B.,Sutton, B.J.,Vila, A.J. Asp-120 locates Zn2 for optimal metallo-beta-lactamase activity. J. Biol. Chem., 282:18276-18285, 2007 Cited by PubMed: 17426028DOI: 10.1074/jbc.M700742200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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