Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0008270 | molecular_function | zinc ion binding |
A | 0008800 | molecular_function | beta-lactamase activity |
A | 0017001 | biological_process | antibiotic catabolic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE GOL A1292 |
Chain | Residue |
A | HIS118 |
A | HOH2280 |
A | HOH2281 |
A | SER120 |
A | HIS196 |
A | GOL1293 |
A | ZN1296 |
A | ZN1297 |
A | HOH2277 |
A | HOH2278 |
A | HOH2279 |
site_id | AC2 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE GOL A1293 |
Chain | Residue |
A | HIS118 |
A | ALA119 |
A | SER120 |
A | CYS221 |
A | GOL1292 |
A | ZN1296 |
A | ZN1297 |
A | HOH2277 |
A | HOH2279 |
A | HOH2280 |
A | HOH2281 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL A1294 |
Chain | Residue |
A | ALA117 |
A | HIS118 |
A | ASN149 |
A | THR197 |
A | ASP199 |
A | ASP236 |
site_id | AC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL A1295 |
Chain | Residue |
A | GLU97 |
A | GLU130 |
A | ARG131 |
A | HOH2077 |
site_id | AC5 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE ZN A1296 |
Chain | Residue |
A | HIS116 |
A | HIS118 |
A | HIS196 |
A | GOL1292 |
A | GOL1293 |
A | HOH2281 |
site_id | AC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE ZN A1297 |
Chain | Residue |
A | CYS221 |
A | HIS263 |
A | GOL1292 |
A | GOL1293 |
A | HOH2280 |
A | HOH2283 |
Functional Information from PROSITE/UniProt
site_id | PS00744 |
Number of Residues | 13 |
Details | BETA_LACTAMASE_B_2 Beta-lactamases class B signature 2. PqynILvGgCLVK |
Chain | Residue | Details |
A | PRO209-LYS224 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | HIS116 | |
A | HIS118 | |
A | HIS196 | |
Chain | Residue | Details |
A | SER120 | |
A | CYS221 | |
A | HIS263 | |
Chain | Residue | Details |
A | LYS224 | |
Chain | Residue | Details |
A | ASN233 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1qh5 |
Chain | Residue | Details |
A | SER120 | |
site_id | MCSA1 |
Number of Residues | 5 |
Details | M-CSA 16 |
Chain | Residue | Details |
A | HIS116 | metal ligand |
A | HIS118 | metal ligand |
A | SER120 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
A | HIS196 | metal ligand |
A | ASN233 | electrostatic stabiliser, hydrogen bond donor |