2UV3
Structure of the signal-regulatory protein (SIRP) alpha domain that binds CD47.
2UV3 の概要
エントリーDOI | 10.2210/pdb2uv3/pdb |
分子名称 | TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, ... (4 entities in total) |
機能のキーワード | cd47-binding domain of sirp-alpha, receptor, membrane, sh3- binding, glycoprotein, transmembrane, phosphorylation, human sirp-alpha n terminal v domain, immunoglobulin domain, signal-regulatory protein alpha |
由来する生物種 | HOMO SAPIENS (HUMAN) |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 28805.98 |
構造登録者 | Hatherley, D.,Harlos, K.,Dunlop, D.C.,Stuart, D.I.,Barclay, A.N. (登録日: 2007-03-08, 公開日: 2007-03-27, 最終更新日: 2024-05-01) |
主引用文献 | Hatherley, D.,Harlos, K.,Dunlop, D.C.,Stuart, D.I.,Barclay, A.N. The Structure of the Macrophage Signal Regulatory Protein Alpha (Sirpalpha) Inhibitory Receptor Reveals a Binding Face Reminiscent of that Used by T Cell Receptors. J.Biol.Chem., 282:14567-, 2007 Cited by PubMed: 17369261DOI: 10.1074/JBC.M611511200 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.8 Å) |
構造検証レポート
検証レポート(詳細版)をダウンロード