2USN
CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN FIBROBLAST STROMELYSIN-1 INHIBITED WITH THIADIAZOLE INHIBITOR PNU-141803
Summary for 2USN
Entry DOI | 10.2210/pdb2usn/pdb |
Descriptor | STROMELYSIN-1, ZINC ION, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | hydrolase, metalloprotease, fibroblast, collagen degradation |
Biological source | Homo sapiens (human) |
Cellular location | Secreted, extracellular space, extracellular matrix : P08254 |
Total number of polymer chains | 1 |
Total formula weight | 19326.65 |
Authors | Finzel, B.C.,Bryant Junior, G.L.,Baldwin, E.T. (deposition date: 1998-06-09, release date: 1998-12-23, Last modification date: 2024-05-22) |
Primary citation | Finzel, B.C.,Baldwin, E.T.,Bryant Jr., G.L.,Hess, G.F.,Wilks, J.W.,Trepod, C.M.,Mott, J.E.,Marshall, V.P.,Petzold, G.L.,Poorman, R.A.,O'Sullivan, T.J.,Schostarez, H.J.,Mitchell, M.A. Structural characterizations of nonpeptidic thiadiazole inhibitors of matrix metalloproteinases reveal the basis for stromelysin selectivity. Protein Sci., 7:2118-2126, 1998 Cited by PubMed: 9792098PDB entries with the same primary citation |
Experimental method |
Structure validation
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