2USN
CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN FIBROBLAST STROMELYSIN-1 INHIBITED WITH THIADIAZOLE INHIBITOR PNU-141803
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | STROMELYSIN-1 | polymer | 165 | 18595.7 | 1 | UniProt (P08254) Pfam (PF00413) | Homo sapiens (human) | MATRIX METALLOPROTEINASE-3, PROTEOGLYCANASE |
| 2 | B, C, G (A) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 3 | D, E, F (A) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 4 | H (A) | [2-(5-MERCAPTO-[1,3,4]THIADIAZOL-2-YLCARBAMOYL)-1-PHENYL-ETHYL]-CARBAMIC ACID BENZYL ESTER | non-polymer | 414.5 | 1 | Chemie (IN8) | |||
| 5 | I (A) | water | water | 18.0 | 84 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18595.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 731.0 | |
| All* | Total formula weight | 19326.6 |
