2ROR

Solution structure of the VAV1 SH2 domain complexed with a tyrosine-phosphorylated peptide from SLP76

Summary for 2ROR

• Entry DOI: 10.2210/pdb2ror/pdb
• Descriptor: Proto-oncogene vav, 15-meric peptide from Lymphocyte cytosolic protein 2 (2 entities in total)
• Functional Keywords: sh2 domain, protein-peptide complex, phosphorylated peptide recognition, phosphotyrosine binding domain, signal transduction, guanine-nucleotide releasing factor, metal-binding, phorbol-ester binding, phosphoprotein, proto-oncogene, sh3 domain, zinc, zinc-finger, signaling protein, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm (Probable): Q13094
• Total number of polymer chains: 2
• Total formula weight: 17289.93

Authors

Tanaka, M.,Kasai, T.,Koshiba, S.,Kigawa, T.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2008-04-08, release date: 2009-04-21, Last modification date: 2022-03-16)

• Primary citation: Kasai, T.,Tanaka, M.,Koshiba, S.,Kigawa, T.,Yokoyama, S.; Solution structure of the VAV1 SH2 domain complexed with a tyrosine-phosphorylated peptide from SLP76; To be Published,

Experimental method

SOLUTION NMR