2ROL

Structural Basis of PxxDY motif recognition in SH3 binding

2ROL の概要

• エントリーDOI: 10.2210/pdb2rol/pdb
• NMR情報: BMRB: 11040
• 分子名称: Epidermal growth factor receptor kinase substrate 8-like protein 1, 12-meric peptide from T-cell surface glycoprotein CD3 epsilon chain (2 entities in total)
• 機能のキーワード: eps8l1, cd3e, sh3, complex structure, alternative splicing, coiled coil, cytoplasm, sh3 domain, immunoglobulin domain, membrane, phosphoprotein, receptor, transmembrane, splicing-signaling protein complex, splicing/signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 8695.70

構造登録者

Aitio, O.,Hellman, M.,Kesti, T.,Kleino, I.,Samuilova, O.,Tossavainen, H.,Paakkonen, K.,Saksela, K.,Permi, P. (登録日: 2008-04-02, 公開日: 2009-03-03, 最終更新日: 2024-05-01)

• 主引用文献: Aitio, O.,Hellman, M.,Kesti, T.,Kleino, I.,Samuilova, O.,Paakkonen, K.,Tossavainen, H.,Saksela, K.,Permi, P.; Structural basis of PxxDY motif recognition in SH3 binding; J.Mol.Biol., 382:167-178, 2008; PubMed: 18644376; DOI: 10.1016/j.jmb.2008.07.008

実験手法

SOLUTION NMR