2ROD
Solution Structure of MCL-1 Complexed with NoxaA
Summary for 2ROD
Entry DOI | 10.2210/pdb2rod/pdb |
Related | 1WSX 2JM6 2ROC |
Descriptor | Induced myeloid leukemia cell differentiation protein Mcl-1 homolog, Noxa (2 entities in total) |
Functional Keywords | mcl-1, noxaa, apoptosis, bh3-only, bcl-2, cytoplasm, developmental protein, differentiation, membrane, mitochondrion, nucleus, phosphoprotein, transmembrane, ubl conjugation |
Biological source | Mus musculus (Mouse) More |
Cellular location | Membrane; Single-pass membrane protein (By similarity): P97287 Mitochondrion: Q9JM54 |
Total number of polymer chains | 2 |
Total formula weight | 21301.16 |
Authors | Day, C.L.,Smits, C.,Fan, F.C.,Lee, E.F.,Fairlie, W.D.,Hinds, M.G. (deposition date: 2008-03-17, release date: 2008-07-08, Last modification date: 2024-05-29) |
Primary citation | Day, C.L.,Smits, C.,Fan, F.C.,Lee, E.F.,Fairlie, W.D.,Hinds, M.G. Structure of the BH3 Domains from the p53-Inducible BH3-Only Proteins Noxa and Puma in Complex with Mcl-1 J.Mol.Biol., 380:958-971, 2008 Cited by PubMed: 18589438DOI: 10.1016/j.jmb.2008.05.071 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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