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2ROC

Solution structure of Mcl-1 Complexed with Puma

Summary for 2ROC
Entry DOI10.2210/pdb2roc/pdb
Related1WSX 2JM6 2ROD
DescriptorInduced myeloid leukemia cell differentiation protein Mcl-1 homolog, Bcl-2-binding component 3 (2 entities in total)
Functional Keywordsmcl-1, bcl-2, apoptosis, puma, bh3-only, cytoplasm, developmental protein, differentiation, membrane, mitochondrion, nucleus, phosphoprotein, transmembrane, ubl conjugation
Biological sourceMus musculus (Mouse)
More
Cellular locationMembrane; Single-pass membrane protein (By similarity): P97287
Mitochondrion: Q99ML1
Total number of polymer chains2
Total formula weight21585.33
Authors
Day, C.L.,Smits, C.,Fan, F.C.,Lee, E.F.,Fairlie, W.D.,Hinds, M.G. (deposition date: 2008-03-17, release date: 2008-07-08, Last modification date: 2021-11-10)
Primary citationDay, C.L.,Smits, C.,Fan, F.C.,Lee, E.F.,Fairlie, W.D.,Hinds, M.G.
Structure of the BH3 Domains from the p53-Inducible BH3-Only Proteins Noxa and Puma in Complex with Mcl-1
J.Mol.Biol., 380:958-971, 2008
Cited by
PubMed: 18589438
DOI: 10.1016/j.jmb.2008.05.071
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

217705

건을2024-03-27부터공개중

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