2ROC
Solution structure of Mcl-1 Complexed with Puma
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Induced myeloid leukemia cell differentiation protein Mcl-1 homolog | polymer | 162 | 18260.7 | 1 | UniProt (P97287) Pfam (PF00452) In PDB | Mus musculus (Mouse) | Bcl-2-related protein EAT/mcl1, Mcl-1 |
2 | B | Bcl-2-binding component 3 | polymer | 27 | 3324.7 | 1 | UniProt (Q99ML1) In PDB | Mus musculus (Mouse) | p53 up-regulated modulator of apoptosis, Puma |
Sequence modifications
A: 152 - 308 (UniProt: P97287)
B: 130 - 155 (UniProt: Q99ML1)
PDB | External Database | Details |
---|---|---|
Gly 147 | - | expression tag |
Pro 148 | - | expression tag |
Leu 149 | - | expression tag |
Gly 150 | - | expression tag |
Ser 151 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ile 144 | Met 144 | engineered mutation |
Met 156 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 21585.3 | |
All* | Total formula weight | 21585.3 |