2RNW

The Structural Basis for Site-Specific Lysine-Acetylated Histone Recognition by the Bromodomains of the Human Transcriptional Co-Activators PCAf and CBP

2RNW の概要

関連するPDBエントリー2RNX
分子名称Histone acetyltransferase PCAF, Histone H3 (2 entities in total)
機能のキーワードbromodomain, histone, acetyltransferase, acyltransferase, cell cycle, host-virus interaction, nucleus, polymorphism, transcription, transcription regulation, acetylation, chromosomal protein, dna damage, dna repair, dna-binding, methylation, nucleosome core, phosphoprotein, transferase-nuclear protein complex, transferase/nuclear protein
由来する生物種Homo sapiens (human)
詳細
細胞内の位置Nucleus (By similarity) Q92831
Nucleus P61830
ポリマー鎖数2
分子量合計15659.05
構造登録者
Zeng, L.,Zhang, Q.,Gerona-Navarro, G.,Zhou, M.M. (登録日: 2008-02-03, 公開日: 2008-05-06, 最終更新日: 2011-07-13)
主引用文献
Zeng, L.,Zhang, Q.,Gerona-Navarro, G.,Moshkina, N.,Zhou, M.M.
Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300
Structure, 16:643-652, 2008
PubMed: 18400184 (主引用文献が同じPDBエントリー)
DOI: 10.1016/j.str.2008.01.010
MImport into Mendeley
実験手法
SOLUTION NMR
NMR情報
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構造検証レポート

ClashscoreRamachandran outliersSidechain outliers815.1%27.2%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
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