2RMV

Solution structure of synthetic 26-mer peptide containing 142-166 sheep prion protein segment and C-terminal cysteine with Y155A mutation

Summary for 2RMV

• Entry DOI: 10.2210/pdb2rmv/pdb
• Related: 2RMW
• Descriptor: Major prion protein (1 entity in total)
• Functional Keywords: tyrosine 155, synthetic prion peptide, disease mutation, glycoprotein, gpi-anchor, lipoprotein, membrane, polymorphism, protein fibril
• Cellular location: Cell membrane; Lipid-anchor, GPI-anchor: P23907
• Total number of polymer chains: 1
• Total formula weight: 3339.63

Authors

Bertho, G.,Bouvier, G.,Hui Bon Hoa, G.,Girault, J.-P. (deposition date: 2007-11-28, release date: 2007-12-18, Last modification date: 2024-05-29)

• Primary citation: Bertho, G.,Bouvier, G.,Hui Bon Hoa, G.,Girault, J.-P.; Key role of the residue 155 in the mechanism of prion transconformation highlighted by the study of sheep mutant peptides; To be Published,

Experimental method

SOLUTION NMR