2RLB

Crystal Structure cation-dependent mannose 6-phosphate receptor at pH 6.5 bound to M6P in absence of Mn

2RLB の概要

• エントリーDOI: 10.2210/pdb2rlb/pdb
• 関連するPDBエントリー: 2RL6 2RL7 2RL8 2RL9
• 分子名称: Cation-dependent mannose-6-phosphate receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-phosphono-beta-D-mannopyranose, ... (4 entities in total)
• 機能のキーワード: p-type lectin, receptor, mannose 6-phosphate, lectin, glycoprotein, lysosome, membrane, transmembrane, transport, protein transport, sugar binding protein
• 由来する生物種: Bos taurus (cattle)
• 細胞内の位置: Lysosome membrane ; Single-pass type I membrane protein : P11456
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 35849.85

構造登録者

Olson, L.J.,Hindsgaul, O.,Dahms, N.M.,Kim, J.-J.P. (登録日: 2007-10-18, 公開日: 2008-02-12, 最終更新日: 2021-10-20)

• 主引用文献: Olson, L.J.,Hindsgaul, O.,Dahms, N.M.,Kim, J.J.; Structural Insights into the Mechanism of pH-dependent Ligand Binding and Release by the Cation-dependent Mannose 6-Phosphate Receptor.; J.Biol.Chem., 283:10124-10134, 2008; PubMed: 18272523; DOI: 10.1074/jbc.M708994200

実験手法

X-RAY DIFFRACTION (1.75 Å)