2RL3
Crystal structure of the OXA-10 W154H mutant at pH 7
Summary for 2RL3
Entry DOI | 10.2210/pdb2rl3/pdb |
Related | 1K4F 2HP5 2HP6 2HP9 2HPB |
Descriptor | Beta-lactamase PSE-2, SULFATE ION, GLYCEROL, ... (5 entities in total) |
Functional Keywords | oxa-10, carboxylated lysine, class d beta-lactamase, antibiotic resistance, hydrolase |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 56516.00 |
Authors | Vercheval, L.,Kerff, F.,Herman, R.,Sauvage, E.,Guiet, R.,Charlier, P.,Frere, J.-M.,Galleni, M. (deposition date: 2007-10-18, release date: 2008-10-28, Last modification date: 2023-11-15) |
Primary citation | Baurin, S.,Vercheval, L.,Bouillenne, F.,Falzone, C.,Brans, A.,Jacquamet, L.,Ferrer, J.L.,Sauvage, E.,Dehareng, D.,Frere, J.M.,Charlier, P.,Galleni, M.,Kerff, F. Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases. Biochemistry, 48:11252-11263, 2009 Cited by PubMed: 19860471DOI: 10.1021/bi901548c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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