2RJL

Crystal structure of human TL1A extracellular domain C95S/C135S mutant

Summary for 2RJL

• Entry DOI: 10.2210/pdb2rjl/pdb
• Related: 2QE3 2RJK
• Descriptor: TNF superfamily ligand TL1A (2 entities in total)
• Functional Keywords: tl1a, tnfsf, cytokine, mutant, membrane, transmembrane
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 20877.62

Authors

Zhan, C.,Patskovsky, Y.,Yan, Q.,Shi, W.,Toro, R.,Bonanno, J.,Nathenson, S.G.,Almo, S.C. (deposition date: 2007-10-15, release date: 2008-08-26, Last modification date: 2023-08-30)

• Primary citation: Zhan, C.,Yan, Q.,Patskovsky, Y.,Li, Z.,Toro, R.,Meyer, A.,Cheng, H.,Brenowitz, M.,Nathenson, S.G.,Almo, S.C.; Biochemical and structural characterization of the human TL1A ectodomain.; Biochemistry, 48:7636-7645, 2009; PubMed: 19522538; DOI: 10.1021/bi900031w

Experimental method

X-RAY DIFFRACTION (2.05 Å)