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2RJL

Crystal structure of human TL1A extracellular domain C95S/C135S mutant

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
TNF superfamily ligand TL1Apolymer18420877.61UniProt (Q8NFE9)
Pfam (PF00229)
UniProt (by SIFTS) (O95150)
Homo sapiens (Human)Tumor necrosis factor Ligand, superfamily, member 15
2B
(A)
waterwater18.072Chemie (HOH)
Sequence modifications
A: 5 - 184 (UniProt: Q8NFE9)
PDBExternal DatabaseDetails
Gly 1-expression tag
Ser 2-expression tag
His 3-expression tag
Met 4-expression tag
Ser 95Cys 162engineered mutation
Ser 135Cys 202engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight20877.6
All*Total formula weight20877.6
*Water molecules are not included.

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PDB entries from 2025-12-24

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