2RJH

Crystal structure of biosynthetic alaine racemase in D-cycloserine-bound form from Escherichia coli

Summary for 2RJH

Entry DOI	10.2210/pdb2rjh/pdb
Related	2RJG
Descriptor	Alanine racemase, SULFATE ION, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE, ... (4 entities in total)
Functional Keywords	alpha/beta barrel, cell shape, cell wall biogenesis/degradation, isomerase, peptidoglycan synthesis, pyridoxal phosphate
Biological source	Escherichia coli
Total number of polymer chains	4
Total formula weight	167574.25
Authors	Wu, D.,Hu, T.,Zhang, L.,Jiang, H.,Shen, X. (deposition date: 2007-10-15, release date: 2008-07-08, Last modification date: 2023-11-15)
Primary citation	Wu, D.,Hu, T.,Zhang, L.,Chen, J.,Du, J.,Ding, J.,Jiang, H.,Shen, X. Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis Protein Sci., 17:1066-1076, 2008 Cited by PubMed: 18434499 DOI: 10.1110/ps.083495908 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation