2RIW
The Reactive loop cleaved human Thyroxine Binding Globulin complexed with thyroxine
Summary for 2RIW
Entry DOI | 10.2210/pdb2riw/pdb |
Related | 2RIV |
Descriptor | Thyroxine-binding globulin, 3,5,3',5'-TETRAIODO-L-THYRONINE, ... (4 entities in total) |
Functional Keywords | thyroxine binding globulin, thyroxine, complex, serpin, tbg, disease mutation, glycoprotein, secreted, signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P05543 P05543 |
Total number of polymer chains | 2 |
Total formula weight | 43269.80 |
Authors | Zhou, A.,Wei, Z.,Stanley, P.L.D.,Read, R.J.,Stein, P.E.,Carrell, R.W. (deposition date: 2007-10-12, release date: 2008-10-14, Last modification date: 2023-11-15) |
Primary citation | Qi, X.,Loiseau, F.,Chan, W.L.,Yan, Y.,Wei, Z.,Milroy, L.G.,Myers, R.M.,Ley, S.V.,Read, R.J.,Carrell, R.W.,Zhou, A. Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins J.Biol.Chem., 286:16163-16173, 2011 Cited by PubMed: 21325280DOI: 10.1074/jbc.M110.171082 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.04 Å) |
Structure validation
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