Crystal Structure of the S112A mutant of a C-C hydrolase, BphD from Burkholderia xenovorans LB400, in complex with 3,10-Di-Fluoro HOPDA

Summary for 2RHW

Related2PUH 2PUJ 2RHT
Descriptor2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase, SODIUM ION, MALONATE ION, ... (5 entities in total)
Functional Keywordsc-c bond hydrolase, hydrolase, aromatic hydrocarbons catabolism
Biological sourceBurkholderia xenovorans
Total number of polymer chains1
Total molecular weight32230.54
Bhowmik, S.,Bolin, J.T. (deposition date: 2007-10-09, release date: 2007-11-13, Last modification date: 2017-10-25)
Primary citation
Bhowmik, S.,Horsman, G.P.,Bolin, J.T.,Eltis, L.D.
The Molecular Basis for Inhibition of BphD, a C-C Bond Hydrolase Involved in Polychlorinated Biphenyls Degradation: LARGE 3-SUBSTITUENTS PREVENT TAUTOMERIZATION.
J.Biol.Chem., 282:36377-36385, 2007
PubMed: 17932031 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M707035200
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.20350.4%1.7%2.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution