2RHB
Crystal structure of Nsp15-H234A mutant- Hexamer in asymmetric unit
2RHB の概要
エントリーDOI | 10.2210/pdb2rhb/pdb |
関連するPDBエントリー | 2gth 2h85 |
分子名称 | Uridylate-specific endoribonuclease (2 entities in total) |
機能のキーワード | endoribonuclease, sars, hexamer, rna, nsp, viral protein |
由来する生物種 | SARS coronavirus |
細胞内の位置 | Non-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity). Helicase: Host endoplasmic reticulum-Golgi intermediate compartment (Potential). Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region (By similarity): P59641 |
タンパク質・核酸の鎖数 | 6 |
化学式量合計 | 236554.76 |
構造登録者 | Palaninathan, S.,Bhardwaj, K.,Alcantara, J.M.O.,Guarino, L.,Yi, L.L.,Kao, C.C.,Sacchettini, J. (登録日: 2007-10-08, 公開日: 2007-11-27, 最終更新日: 2023-08-30) |
主引用文献 | Bhardwaj, K.,Palaninathan, S.,Alcantara, J.M.,Yi, L.L.,Guarino, L.,Sacchettini, J.C.,Kao, C.C. Structural and functional analyses of the severe acute respiratory syndrome coronavirus endoribonuclease Nsp15. J.Biol.Chem., 283:3655-3664, 2008 Cited by PubMed: 18045871DOI: 10.1074/jbc.M708375200 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.8 Å) |
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