2RF5

Crystal structure of human tankyrase 1- catalytic PARP domain

Summary for 2RF5

DescriptorTankyrase-1, ZINC ION, GLYCEROL, ... (4 entities in total)
Functional Keywordscatalytic fragment, parp, structural genomics, structural genomics consortium, sgc, adp-ribosylation, ank repeat, chromosomal protein, glycosyltransferase, golgi apparatus, membrane, mrna transport, nad, nuclear pore complex, nucleus, phosphorylation, protein transport, telomere, transferase, translocation, transport
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm O95271
Total number of polymer chains1
Total molecular weight29574.59
Authors
Primary citation
Lehtio, L.,Collins, R.,van den Berg, S.,Johansson, A.,Dahlgren, L.G.,Hammarstrom, M.,Helleday, T.,Holmberg-Schiavone, L.,Karlberg, T.,Weigelt, J.
Zinc binding catalytic domain of human tankyrase 1.
J.Mol.Biol., 379:136-145, 2008
PubMed: 18436240 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2008.03.058
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.251203.5%2.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution