2RDK

Five site mutated Cyanovirin-N with Mannose dimer bound

Summary for 2RDK

• Entry DOI: 10.2210/pdb2rdk/pdb
• Related: 1IIY 1LOM 1M5M 2PYS 2Z21 3EZM
• Related PRD ID: PRD_900111
• Descriptor: Cyanovirin-N, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose (3 entities in total)
• Functional Keywords: cyanovirin-n, sugar binding protein, anti hiv, antiviral protein, protein synthesis inhibitor
• Biological source: Nostoc ellipsosporum
• Total number of polymer chains: 2
• Total formula weight: 24582.78

Authors

Fromme, R.,Katiliene, Z.,Fromme, P.,Ghirlanda, G. (deposition date: 2007-09-24, release date: 2008-05-06, Last modification date: 2023-08-30)

• Primary citation: Fromme, R.,Katiliene, Z.,Fromme, P.,Ghirlanda, G.; Conformational gating of dimannose binding to the antiviral protein cyanovirin revealed from the crystal structure at 1.35 A resolution.; Protein Sci., 17:939-944, 2008; PubMed: 18436959; DOI: 10.1110/ps.083472808

Experimental method

X-RAY DIFFRACTION (1.35 Å)