2RAH

Human FDPS synthase in complex with novel inhibitor

Summary for 2RAH

• Entry DOI: 10.2210/pdb2rah/pdb
• Related: 1ZW5
• Descriptor: Farnesyl pyrophosphate synthetase, MAGNESIUM ION, SULFATE ION, ... (5 entities in total)
• Functional Keywords: mainly alpha, orthogonal bundle, osteoporosis, cholesterol biosynthesis, cytoplasm, host-virus interaction, isoprene biosynthesis, lipid synthesis, steroid biosynthesis, sterol biosynthesis, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P14324
• Total number of polymer chains: 1
• Total formula weight: 43900.89

Authors

Evdokimov, A.G.,Barnett, B.L.,Ebetino, F.H.,Pokross, M. (deposition date: 2007-09-15, release date: 2007-09-25, Last modification date: 2023-08-30)

• Primary citation: Evdokimov, A.G.,Barnett, B.L.,Ebetino, F.H.,Pokross, M.; Human FDPS synthase in complex with novel inhibitor; To be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)