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2R9B

Structural Analysis of Plasmepsin 2 from Plasmodium falciparum complexed with a peptide-based inhibitor

Summary for 2R9B
Entry DOI10.2210/pdb2r9b/pdb
Related PRD IDPRD_000306
DescriptorPlasmepsin-2, peptide-based inhibitor (3 entities in total)
Functional Keywordsbeta fold aspartyl protease, glycoprotein, vacuole, zymogen, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourcePlasmodium falciparum
More
Cellular locationVacuole: P46925
Total number of polymer chains4
Total formula weight75839.86
Authors
Liu, P.,Marzahn, M.R.,Robbins, A.H.,McKenna, R.,Dunn, B.M. (deposition date: 2007-09-12, release date: 2007-11-27, Last modification date: 2023-11-15)
Primary citationLiu, P.,Marzahn, M.R.,Robbins, A.H.,Gutierrez-de-Teran, H.,Rodriguez, D.,McClung, S.H.,Stevens, S.M.,Yowell, C.A.,Dame, J.B.,McKenna, R.,Dunn, B.M.
Recombinant plasmepsin 1 from the human malaria parasite plasmodium falciparum: enzymatic characterization, active site inhibitor design, and structural analysis.
Biochemistry, 48:4086-4099, 2009
Cited by
PubMed: 19271776
DOI: 10.1021/bi802059r
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

217705

건을2024-03-27부터공개중

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