2R7E
Crystal Structure Analysis of Coagulation Factor VIII
Summary for 2R7E
Entry DOI | 10.2210/pdb2r7e/pdb |
Related | 1d7p |
Descriptor | Coagulation factor VIII, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | ceruloplasmin fold, cupper protein fold, c2 domain fold, acute phase, blood coagulation, disease mutation, glycoprotein, hemophilia, metal-binding, secreted, sulfation, blood clotting |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 176523.07 |
Authors | Stoddard, B.L.,Shen, B.W. (deposition date: 2007-09-07, release date: 2008-04-15, Last modification date: 2023-08-30) |
Primary citation | Shen, B.W.,Spiegel, P.C.,Chang, C.H.,Huh, J.W.,Lee, J.S.,Kim, J.,Kim, Y.H.,Stoddard, B.L. The tertiary structure and domain organization of coagulation factor VIII. Blood, 111:1240-1247, 2008 Cited by PubMed: 17965321DOI: 10.1182/blood-2007-08-109918 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.7 Å) |
Structure validation
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