2R5Q
Crystal Structure Analysis of HIV-1 Subtype C Protease Complexed with Nelfinavir
Summary for 2R5Q
| Entry DOI | 10.2210/pdb2r5q/pdb |
| Related | 2R5P |
| Descriptor | Protease, 2-[2-HYDROXY-3-(3-HYDROXY-2-METHYL-BENZOYLAMINO)-4-PHENYL SULFANYL-BUTYL]-DECAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID TERT-BUTYLAMIDE (3 entities in total) |
| Functional Keywords | hiv-1 subtype c, aspartyl protease, hydrolase, protease, viral protein |
| Biological source | Human immunodeficiency virus 1 |
| Total number of polymer chains | 4 |
| Total formula weight | 44142.71 |
| Authors | Coman, R.M.,Robbins, A.H.,McKenna, R.,Dunn, B.M. (deposition date: 2007-09-04, release date: 2007-11-20, Last modification date: 2024-02-21) |
| Primary citation | Coman, R.M.,Robbins, A.H.,Fernandez, M.A.,Gilliland, C.T.,Sochet, A.A.,Goodenow, M.M.,McKenna, R.,Dunn, B.M. The Contribution of Naturally Occurring Polymorphisms in Altering the Biochemical and Structural Characteristics of HIV-1 Subtype C Protease Biochemistry, 47:731-743, 2008 Cited by PubMed: 18092815DOI: 10.1021/bi7018332 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report
