2R5A

Crystal Structure of the two MBT repeats from Sex-Comb on Midleg (SCM) in complex with methyl lysine

Summary for 2R5A

Entry DOI	10.2210/pdb2r5a/pdb
Related	2R57 2R58 2R5M
Descriptor	Polycomb protein Scm, N-METHYL-LYSINE (3 entities in total)
Functional Keywords	mbt repeat, polycomb, sex comb on midleg, scm, mbt, chromatin regulator, developmental protein, metal-binding, nucleus, repressor, transcription, transcription regulation
Biological source	Drosophila melanogaster (fruit fly)
Cellular location	Nucleus (Probable): Q9VHA0
Total number of polymer chains	1
Total formula weight	29558.52
Authors	Grimm, C.,Steuerwald, U.,Mueller, C.W. (deposition date: 2007-09-03, release date: 2007-10-30, Last modification date: 2024-02-21)
Primary citation	Grimm, C.,de Ayala Alonso, A.G.,Rybin, V.,Steuerwald, U.,Ly-Hartig, N.,Fischle, W.,Muller, J.,Muller, C.W. Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg. Embo Rep., 8:1031-1037, 2007 Cited by PubMed: 17932512 DOI: 10.1038/sj.embor.7401085 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation