2R27
Constitutively zinc-deficient mutant of human superoxide dismutase (SOD), C6A, H80S, H83S, C111S
Summary for 2R27
Entry DOI | 10.2210/pdb2r27/pdb |
Descriptor | Superoxide dismutase [Cu-Zn], COPPER (II) ION (3 entities in total) |
Functional Keywords | oxidoreductase, beta barrel, cu ion, amyotrophic lateral sclerosis, antioxidant, disease mutation, metal-binding |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00441 |
Total number of polymer chains | 2 |
Total formula weight | 31790.19 |
Authors | Roberts, B.R.,Getzoff, E.D.,Karplus, P.A.,Beckman, J.S.,Tainer, J.A. (deposition date: 2007-08-24, release date: 2007-12-11, Last modification date: 2023-08-30) |
Primary citation | Roberts, B.R.,Tainer, J.A.,Getzoff, E.D.,Malencik, D.A.,Anderson, S.R.,Bomben, V.C.,Meyers, K.R.,Karplus, P.A.,Beckman, J.S. Structural characterization of zinc-deficient human superoxide dismutase and implications for ALS. J.Mol.Biol., 373:877-890, 2007 Cited by PubMed: 17888947DOI: 10.1016/j.jmb.2007.07.043 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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