2R09
Crystal Structure of Autoinhibited Form of Grp1 Arf GTPase Exchange Factor
Summary for 2R09
Entry DOI | 10.2210/pdb2r09/pdb |
Related | 2r0d |
Descriptor | Cytohesin-3, SULFATE ION, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, ... (6 entities in total) |
Functional Keywords | autoinhibition, grp1, pip3, arf, 3-phosphoinositide, pleckstrin homology domain, guanine-nucleotide releasing factor, signaling protein |
Biological source | Mus musculus (house mouse) |
Cellular location | Cell membrane (By similarity): O08967 |
Total number of polymer chains | 2 |
Total formula weight | 83897.29 |
Authors | DiNitto, J.P.,Delprato, A.,Gabe Lee, M.T.,Cronin, T.C.,Huang, S.,Guilherme, A.,Czech, M.P.,Lambright, D.G. (deposition date: 2007-08-17, release date: 2007-12-04, Last modification date: 2021-10-20) |
Primary citation | DiNitto, J.P.,Delprato, A.,Gabe Lee, M.T.,Cronin, T.C.,Huang, S.,Guilherme, A.,Czech, M.P.,Lambright, D.G. Structural Basis and Mechanism of Autoregulation in 3-Phosphoinositide-Dependent Grp1 Family Arf GTPase Exchange Factors. Mol.Cell, 28:569-583, 2007 Cited by PubMed: 18042453DOI: 10.1016/j.molcel.2007.09.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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