2R02

Crystal Structure of ALIX/AIP1 in complex with the HIV-1 YPLTSL Late Domain

2R02 の概要

• エントリーDOI: 10.2210/pdb2r02/pdb
• 関連するPDBエントリー: 2R03 2R05
• 分子名称: Programmed cell death 6-interacting protein, p6-gag (3 entities in total)
• 機能のキーワード: coiled-coil, apoptosis, cytoplasm, host-virus interaction, polymorphism, protein transport, transport, aids, capsid protein, lipoprotein, membrane, metal-binding, myristate, nucleus, phosphorylation, rna-binding, viral nucleoprotein, virion, zinc, zinc-finger
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm, cytosol : Q8WUM4; Gag polyprotein: Host cell membrane ; Lipid-anchor . Matrix protein p17: Virion membrane ; Lipid-anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion : Q9WC62
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 79367.17

構造登録者

Hill, C.P.,Zhai, Q.,Fisher, R.D. (登録日: 2007-08-17, 公開日: 2007-12-18, 最終更新日: 2024-02-21)

• 主引用文献: Zhai, Q.,Fisher, R.D.,Chung, H.Y.,Myszka, D.G.,Sundquist, W.I.,Hill, C.P.; Structural and functional studies of ALIX interactions with YPX(n)L late domains of HIV-1 and EIAV.; Nat.Struct.Mol.Biol., 15:43-49, 2008; PubMed: 18066081; DOI: 10.1038/nsmb1319

実験手法

X-RAY DIFFRACTION (2.6 Å)