2QYF

Crystal structure of the Mad2/p31(comet)/Mad2-binding peptide ternary complex

Summary for 2QYF

Entry DOI	10.2210/pdb2qyf/pdb
Related	1DUJ 1KLQ 1S2H
Descriptor	Mitotic spindle assembly checkpoint protein MAD2A, MAD2L1-binding protein, peptide, ... (4 entities in total)
Functional Keywords	protein-peptide complex, mad2 family, spindle assembly checkpoint, cell cycle, cell division, mitosis, nucleus, phosphorylation
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: Q13257 Q15013
Total number of polymer chains	6
Total formula weight	105470.54
Authors	Tomchick, D.R.,Luo, X. (deposition date: 2007-08-14, release date: 2008-01-29, Last modification date: 2021-10-20)
Primary citation	Yang, M.,Li, B.,Tomchick, D.R.,Machius, M.,Rizo, J.,Yu, H.,Luo, X. p31comet blocks Mad2 activation through structural mimicry. Cell(Cambridge,Mass.), 131:744-755, 2007 Cited by PubMed: 18022368 DOI: 10.1016/j.cell.2007.08.048 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation