2QYF

Crystal structure of the Mad2/p31(comet)/Mad2-binding peptide ternary complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Mitotic spindle assembly checkpoint protein MAD2A	polymer	206	23595.8	2	UniProt (Q13257) Pfam (PF02301)	Homo sapiens (human)	MAD2-like 1, HsMAD2
2	B, D (B, D)	MAD2L1-binding protein	polymer	240	27687.9	2	UniProt (Q15013) Pfam (PF06581)	Homo sapiens (human)	Caught by MAD2 protein
3	E, F (E, F)	peptide	polymer	12	1451.6	2
4	G, H, I, J, K... (A, B, C, D, E...)	water	water		18.0	658	Chemie (HOH)

Sequence modifications

A, C: 1 - 205 (UniProt: Q13257)

PDB	External Database	Details
Gly 0	-	expression tag
Ala 13	Leu 13	engineered mutation

B, D: 36 - 274 (UniProt: Q15013)

PDB	External Database	Details
Mse 35	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	105470.5
All*	Total formula weight	105470.5

*Water molecules are not included.