2QXI
High resolution structure of Human Kallikrein 7 in Complex with Suc-Ala-Ala-Pro-Phe-chloromethylketone
Summary for 2QXI
Entry DOI | 10.2210/pdb2qxi/pdb |
Related | 2QXG 2QXH 2QXJ |
Descriptor | Kallikrein-7, N-(3-carboxypropanoyl)-L-alanyl-L-alanyl-N-[(2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl]-L-prolinamide (3 entities in total) |
Functional Keywords | s1 pocket, chloromethyl ketone, alternate conformations, alternative splicing, glycoprotein, hydrolase, protease, secreted, serine protease, zymogen |
Biological source | Homo sapiens (human) |
Cellular location | Secreted : P49862 |
Total number of polymer chains | 1 |
Total formula weight | 25020.18 |
Authors | Debela, M.,Hess, P.,Magdolen, V.,Schechter, N.M.,Bode, W.,Goettig, P. (deposition date: 2007-08-11, release date: 2008-01-08, Last modification date: 2023-08-30) |
Primary citation | Debela, M.,Hess, P.,Magdolen, V.,Schechter, N.M.,Steiner, T.,Huber, R.,Bode, W.,Goettig, P. Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7. Proc.Natl.Acad.Sci.Usa, 104:16086-16091, 2007 Cited by PubMed: 17909180DOI: 10.1073/pnas.0707811104 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1 Å) |
Structure validation
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