2QUX

PP7 coat protein dimer in complex with RNA hairpin

2QUX の概要

• エントリーDOI: 10.2210/pdb2qux/pdb
• 関連するPDBエントリー: 1DWN 2QUD
• 分子名称: RNA (25-MER), Coat protein, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: bacteriophage coat protein, rna-protein complex, capsid protein, structural protein-rna complex, structural protein/rna
• 由来する生物種: Pseudomonas phage PP7; 詳細
• タンパク質・核酸の鎖数: 18
• 化学式量合計: 213102.19

構造登録者

Chao, J.A. (登録日: 2007-08-06, 公開日: 2007-12-18, 最終更新日: 2023-08-30)

主引用文献

Chao, J.A.,Patskovsky, Y.,Almo, S.C.,Singer, R.H.
Structural basis for the coevolution of a viral RNA-protein complex.
Nat.Struct.Mol.Biol., 15:103-105, 2008

PubMed Abstract: The cocrystal structure of the PP7 bacteriophage coat protein in complex with its translational operator identifies a distinct mode of sequence-specific RNA recognition when compared to the well-characterized MS2 coat protein-RNA complex. The structure reveals the molecular basis of the PP7 coat protein's ability to selectively bind its cognate RNA, and it demonstrates that the conserved beta-sheet surface is a flexible architecture that can evolve to recognize diverse RNA hairpins.

PubMed: 18066080
DOI: 10.1038/nsmb1327

実験手法

X-RAY DIFFRACTION (2.44 Å)