2QUE

Saturation of substrate-binding site using two natural ligands: Crystal structure of a ternary complex of phospholipase A2 with anisic acid and ajmaline at 2.25 A resolution

Summary for 2QUE

• Entry DOI: 10.2210/pdb2que/pdb
• Related: 2OTH 2OUB 2PYC
• Descriptor: Phospholipase A2 VRV-PL-VIIIa, AJMALINE, 4-METHOXYBENZOIC ACID, ... (4 entities in total)
• Functional Keywords: active site, lipid hydrolysis, binding affinity, calcium, hydrolase, lipid degradation, metal-binding, neurotoxin, presynaptic neurotoxin, secreted, toxin
• Biological source: Daboia russellii pulchella (RUSSELL'S VIPER)
• Cellular location: Secreted: P59071
• Total number of polymer chains: 1
• Total formula weight: 14080.29

Authors

Kumar, S.,Singh, N.,Sharma, S.,Kaur, P.,Singh, T.P. (deposition date: 2007-08-05, release date: 2007-08-14, Last modification date: 2024-10-30)

• Primary citation: Kumar, S.,Singh, N.,Sharma, S.,Kaur, P.,Singh, T.P.; Saturation of substrate-binding site using two natural ligands: Crystal structure of a ternary complex of phospholipase A2 with anisic acid and ajmaline at 2.25 A resolution; To be Published,

Experimental method

X-RAY DIFFRACTION (2.25 Å)