2QS3

Crystal structure of the GluR5 ligand binding core dimer in complex with UBP316 at 1.76 Angstroms resolution

2QS3 の概要

• エントリーDOI: 10.2210/pdb2qs3/pdb
• 関連するPDBエントリー: 1TXF 2F34 2F35 2F36 2QS1 2QS2 2QS4
• 分子名称: Glutamate receptor, ionotropic kainate 1, CHLORIDE ION, PENTAETHYLENE GLYCOL, ... (5 entities in total)
• 機能のキーワード: membrane protein, cell junction, glycoprotein, ion transport, ionic channel, phosphorylation, postsynaptic cell membrane, receptor, rna editing, synapse, transmembrane, transport
• 由来する生物種: Rattus norvegicus (rat); 詳細
• 細胞内の位置: Cell membrane; Multi-pass membrane protein: P22756
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 59829.42

構造登録者

Alushin, G.M.,Jane, D.E.,Mayer, M.L. (登録日: 2007-07-30, 公開日: 2008-08-05, 最終更新日: 2023-08-30)

• 主引用文献: Dargan, S.L.,Clarke, V.R.,Alushin, G.M.,Sherwood, J.L.,Nistico, R.,Bortolotto, Z.A.,Ogden, A.M.,Bleakman, D.,Doherty, A.J.,Lodge, D.,Mayer, M.L.,Fitzjohn, S.M.,Jane, D.E.,Collingridge, G.L.; ACET is a highly potent and specific kainate receptor antagonist: characterisation and effects on hippocampal mossy fibre function.; Neuropharmacology, 56:121-130, 2009; PubMed: 18789344; DOI: 10.1016/j.neuropharm.2008.08.016

実験手法

X-RAY DIFFRACTION (1.76 Å)