2QS1

Crystal structure of the GluR5 ligand binding core dimer in complex with UBP315 at 1.80 Angstroms resolution

2QS1 の概要

• エントリーDOI: 10.2210/pdb2qs1/pdb
• 関連するPDBエントリー: 1TXF 2F34 2F35 2F36 2QS2 2QS3 2QS4
• 分子名称: Glutamate receptor, ionotropic kainate 1, CHLORIDE ION, PENTAETHYLENE GLYCOL, ... (5 entities in total)
• 機能のキーワード: membrane protein, cell junction, glycoprotein, ion transport, ionic channel, phosphorylation, postsynaptic cell membrane, receptor, rna editing, synapse, transmembrane, transport
• 由来する生物種: Rattus norvegicus (rat); 詳細
• 細胞内の位置: Cell membrane; Multi-pass membrane protein: P22756
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 59992.81

構造登録者

Alushin, G.M.,Jane, D.E.,Mayer, M.L. (登録日: 2007-07-30, 公開日: 2008-08-05, 最終更新日: 2023-08-30)

• 主引用文献: Alushin, G.M.,Jane, D.,Mayer, M.L.; Binding site and ligand flexibility revealed by high resolution crystal structures of GluK1 competitive antagonists.; Neuropharmacology, 60:126-134, 2011; PubMed: 20558186; DOI: 10.1016/j.neuropharm.2010.06.002

実験手法

X-RAY DIFFRACTION (1.8 Å)