2QOQ

Human EphA3 kinase and juxtamembrane region, base, AMP-PNP bound structure

2QOQ の概要

• エントリーDOI: 10.2210/pdb2qoq/pdb
• 関連するPDBエントリー: 2GSF 2QO2 2QO7 2QO9 2QOB 2QOC 2QOD 2QOF 2QOI 2QOK 2QOL 2QON 2QOO
• 分子名称: Ephrin receptor, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total)
• 機能のキーワード: receptor tyrosine kinase, structural genomics, juxtamembrane segment, amp-pnp, structural genomics consortium, sgc, atp-binding, nucleotide-binding, phosphorylation, transferase, transmembrane, tyrosine-protein kinase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42574.34

構造登録者

Davis, T.,Walker, J.R.,Newman, E.M.,Mackenzie, F.,Butler-Cole, C.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.,Loppnau, P.,Allali-Hassani, A.,Structural Genomics Consortium (SGC) (登録日: 2007-07-20, 公開日: 2007-10-02, 最終更新日: 2023-11-15)

• 主引用文献: Davis, T.L.,Walker, J.R.,Loppnau, P.,Butler-Cole, C.,Allali-Hassani, A.,Dhe-Paganon, S.; Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).; Structure, 16:873-884, 2008; PubMed: 18547520; DOI: 10.1016/j.str.2008.03.008

実験手法

X-RAY DIFFRACTION (1.6 Å)