2QNV

Crystal Structure of the Pregnane X Receptor bound to Colupulone

Summary for 2QNV

• Entry DOI: 10.2210/pdb2qnv/pdb
• Descriptor: Orphan nuclear receptor PXR, 3,5-dihydroxy-4,6,6-tris(3-methylbut-2-en-1-yl)-2-(2-methylpropanoyl)cyclohexa-2,4-dien-1-one (3 entities in total)
• Functional Keywords: alpha helical sandwhich, protein-ligand complex, alternative splicing, dna-binding, metal-binding, nucleus, polymorphism, receptor, transcription, transcription regulation, zinc-finger, nuclear protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 36681.42

Authors

Teotico, D.G.,Bischof, J.,Redinbo, M.R. (deposition date: 2007-07-19, release date: 2008-07-29, Last modification date: 2023-08-30)

• Primary citation: Teotico, D.G.,Bischof, J.,Redinbo, M.R.; Crystal Structure of the Pregnane X Receptor bound to Colupulone; TO BE PUBLISHED,

Experimental method

X-RAY DIFFRACTION (2.8 Å)