2QN1
Glycogen Phosphorylase b in complex with asiatic acid
Summary for 2QN1
Entry DOI | 10.2210/pdb2qn1/pdb |
Related | 2QN2 |
Descriptor | Glycogen phosphorylase, muscle form, asiatic acid (3 entities in total) |
Functional Keywords | glycogenolysis, type 2 diabetes, transferase, apoptosis |
Biological source | Oryctolagus cuniculus (rabbit) |
Total number of polymer chains | 1 |
Total formula weight | 98008.02 |
Authors | Zographos, S.E.,Leonidas, D.D.,Alexacou, K.-M.,Hayes, J.,Oikonomakos, N.G. (deposition date: 2007-07-17, release date: 2008-06-03, Last modification date: 2023-11-15) |
Primary citation | Wen, X.,Sun, H.,Liu, J.,Cheng, K.,Zhang, P.,Zhang, L.,Hao, J.,Zhang, L.,Ni, P.,Zographos, S.E.,Leonidas, D.D.,Alexacou, K.-M.,Gimisis, T.,Hayes, J.M.,Oikonomakos, N.G. Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies J.Med.Chem., 51:3540-3554, 2008 Cited by PubMed: 18517260DOI: 10.1021/jm8000949 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.401 Å) |
Structure validation
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