2QLN

Glycogen Phosphorylase b in complex with N-4-phenylbenzoyl-N'-beta-D-glucopyranosyl urea

Summary for 2QLN

• Entry DOI: 10.2210/pdb2qln/pdb
• Related: 2QLM 2QN3 2QN7 2QN8 2QN9 2QNB
• Descriptor: Glycogen phosphorylase, muscle form, N-[(biphenyl-4-ylcarbonyl)carbamoyl]-beta-D-glucopyranosylamine (3 entities in total)
• Functional Keywords: glycogenolysis, type 2 diabetes, acetylation, allosteric enzyme, carbohydrate metabolism, glycogen metabolism, glycosyltransferase, nucleotide-binding, phosphoprotein, pyridoxal phosphate, transferase
• Biological source: Oryctolagus cuniculus (Rabbit)
• Total number of polymer chains: 1
• Total formula weight: 97921.72

Authors

Oikonomakos, N.G.,Chrysina, E.D.,Tiraidis, C.,Alexacou, K.-M.,Leonidas, D.D.,Sographos, S.E. (deposition date: 2007-07-13, release date: 2008-07-15, Last modification date: 2023-11-15)

• Primary citation: Nagy, V.,Felf ldi, N.,Praly, J.-P.,Dosca, T.,Gergerly, P.,Chrysina, E.D.,Tiraidis, C.,Kosmopoulou, M.N.,Alexacou, K.-M.,Konstantakaki, M.; N-(4-substituted-benzoyl)-N'-(beta-D-glucopyranosyl)ureas, inhibitors of glycogen phosphorylase: synthesis, kinetic and crystallographic evaluation; To be Published,

Experimental method

X-RAY DIFFRACTION (2.15 Å)