2QL2

Crystal Structure of the basic-helix-loop-helix domains of the heterodimer E47/NeuroD1 bound to DNA

2QL2 の概要

• エントリーDOI: 10.2210/pdb2ql2/pdb
• 分子名称: Transcription factor E2-alpha, Neurogenic differentiation factor 1, DNA (5'-D(*DTP*DAP*DGP*DGP*DCP*DCP*DAP*DTP*DCP*DTP*DGP*DGP*DTP*DCP*DCP*DT)-3'), ... (5 entities in total)
• 機能のキーワード: basic-helix-loop-helix, protein-dna complex, heterodimer, dna-binding, activator, developmental protein, differentiation, neurogenesis, nucleus, phosphorylation, transcription, transcription regulation, cytoplasm, phosphoprotein, transcription-dna complex, transcription/dna
• 由来する生物種: Mus musculus (Mouse); 詳細
• 細胞内の位置: Cytoplasm (By similarity): 2QL2
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 47849.93

構造登録者

Rose, R.B.,Longo, A.,Guanga, G.P. (登録日: 2007-07-12, 公開日: 2008-11-04, 最終更新日: 2023-08-30)

• 主引用文献: Longo, A.,Guanga, G.P.,Rose, R.B.; Crystal structure of E47-NeuroD1/beta2 bHLH domain-DNA complex: heterodimer selectivity and DNA recognition.; Biochemistry, 47:218-229, 2008; PubMed: 18069799; DOI: 10.1021/bi701527r

実験手法

X-RAY DIFFRACTION (2.5 Å)